Ready and Abl

Are acute stroke-ready hospitals ready?

I n 2005, an American Stroke Association Task Force report described the rationale and components of an integrated stroke system of care extending from primordial prevention through primary prevention, acute management, secondary prevention, and poststroke rehabilitation and recovery. 1 The principle that optimal patient outcomes depend on the consistent implementation of care processes that ar...

BCR-ABL and Human Cancer

The BCR-ABL oncogene was the first chromosomal abnormality shown to be associated with a specific human malignancy, the chronic myelogenous leukemia (CML), resulting from a reciprocal t(9;22) translocation characterized by the formation of a shortened chromosome, named Philadelphia chromosome (Ph), in which the tyrosine kinase of c-ABL is constitutively activated. This chromosomal translocation...

Ready Reckoners

Figure 1 Webster Front Page 1634 ..................................................................................................................... 2 Figure 2 Webster's 1634 Compound Interest Table............................................................................................ 2 Figure 3 Frontispiece of Barreme, 1762 ..................................................................

Slocum Gliders: Robust and ready

More Cables to Abl

Previews contains an area of weak homology to cyclin A and More Cables to Abl cyclin C. The authors went on to show that Cables bound to Cdk5 and that it could function as a substrate for phosphorylation by the Cdk5/p35 kinase. Interestingly, there appears to be some form of competition for bind-Life is complex. Take for example the abelson gene, ing to Cdk5 in that Cdk5/Cables and Cdk5/p35 pro...